Androgenetic alopecia (AGA) is the medical name for pattern hair loss – the most common form in both men and women. It is driven by a genetic sensitivity to dihydrotestosterone (DHT), a potent androgen derived from testosterone through the action of 5-alpha reductase.
In genetically susceptible individuals, DHT binds to receptors in the hair follicle and triggers miniaturization: the follicle progressively produces thinner, shorter, and less pigmented hairs over successive growth cycles, eventually becoming inactive. This occurs selectively – the hairline and crown in men, the central scalp in women – while follicles at the back and sides of the scalp remain resistant. That resistance is what makes surgical hair restoration possible: donor follicles retain their DHT-resistant characteristics even after transplantation.
Androgenetic alopecia in men is classified using the Norwood-Hamilton scale, a seven-stage system describing progression from early temporal recession to advanced vertex and crown loss. Norwood staging is one factor that guides treatment recommendations - not because every stage has a predetermined answer, but because it provides a framework for where a patient currently is and where loss may progress.
In women, androgenetic alopecia typically presents as diffuse thinning over the central scalp rather than the hairline recession seen in men. The Ludwig scale classifies female pattern hair loss across three stages. Women are also susceptible to other types of hair loss that can mimic or occur alongside AGA, which is why thorough evaluation is particularly important in female patients.
Alopecia areata is an autoimmune condition in which the immune system attacks the hair follicle, producing distinct circular patches of hair loss. It can affect any hair-bearing area and ranges from isolated patches to complete scalp or body hair loss. Treatment approaches for alopecia areata are distinct from those for androgenetic alopecia and require specialist evaluation.
The treatment appropriate for androgenetic alopecia is not appropriate for telogen effluvium. The approach to traction alopecia differs from the approach to alopecia areata. Before any treatment is recommended at Sage Hair Clinic, Dr. Patel conducts an evaluation to understand the type and cause of each patient’s hair loss.